Imipramine
In stock
75mg · 50mg · 25mg
from A$51.19
In brief
Imipramine, sold in Australia as Tofranil, is a tricyclic antidepressant used for major depression and for bed-wetting in children from the age of 5 when physical causes have been ruled out.
What is imipramine used for?
Imipramine is a tricyclic antidepressant. healthdirect lists Tofranil (imipramine hydrochloride) for major depression and for night-time bed-wetting from the age of 5, once physical causes have been ruled out.
This listing shows imipramine 25 mg, 50 mg and 75 mg. It does not name the manufacturer of the tablets supplied, so check the label on the pack you receive and confirm with your prescriber or pharmacist that it matches your prescription.
Imipramine and Tofranil
Imipramine is the active ingredient; Tofranil is the brand. In Australia, Tofranil is supplied by Amdipharm Mercury as 10 mg and 25 mg sugar-coated tablets. It is a Schedule 4 (Prescription Only) medicine and is subsidised on the PBS. The 50 mg and 75 mg strengths on this page are not among the Tofranil strengths listed by healthdirect.
How long does imipramine take to work?
According to the Tofranil consumer medicine information, it can take up to 4 to 6 weeks to feel any real improvement. Do not stop taking it without checking with your doctor first.
Who should not take imipramine
- Anyone allergic to imipramine or another tricyclic antidepressant
- People taking an MAO inhibitor; after stopping one, wait two weeks before starting imipramine
- People recovering from a recent heart attack
Important warnings
The Tofranil consumer information warns of a risk of suicidal thoughts, especially in young people. Contact your doctor immediately if these occur.
Extra care is needed with glaucoma, urinary problems, seizures and heart conditions. Avoid alcohol, and do not drive until you know how imipramine affects you. People over 65 face particular risks and should discuss them with their doctor. If you are pregnant, seek advice from your doctor or pharmacist.
Imipramine side effects
Common side effects include drowsiness, dizziness, dry mouth, constipation, weight gain, sexual problems and blurred vision.
Serious side effects listed in the consumer information include allergic reactions, irregular heartbeat, severe confusion and uncontrolled movements.
Imipramine interactions
The Tofranil consumer information names MAO inhibitors, blood pressure medicines, SSRI antidepressants, seizure medicines, warfarin, some cold medicines and nicotine products.
Storage
Tofranil is stored below 30 °C and protected from moisture. Follow the storage directions on the pack you receive.
Imipramine price: compare pack sizes
Compare packs of the same strength. These examples are for 25 mg and are calculated from the listed prices at the shop’s Australian-dollar rate on 7 October 2026, before delivery or other checkout charges.
| Strength | Pack size | Pack price | Price per tablet |
|---|---|---|---|
| 25 mg | 30 | A$51.56 | A$1.72 |
| 25 mg | 90 | A$97.40 | A$1.08 |
| 25 mg | 360 | A$263.58 | A$0.73 |
At 25 mg, the 90 pack costs about 37.0% less per tablet than the 30 pack, and the 360 pack about 57.4% less.
A lower price per tablet means a larger upfront payment. Choose only the quantity and strength appropriate to your prescription, and check the expiry date. Prices can change, so confirm the current pack price before ordering.
Frequently asked questions
Is imipramine the same as Tofranil?
Tofranil is a brand of imipramine hydrochloride.
Is imipramine used for bed-wetting?
Yes, in children from the age of 5, once physical causes have been ruled out.
Can I drink alcohol while taking imipramine?
The consumer information advises avoiding alcohol.
Delivery across Australia
Airmail service: delivery in 14–22 days, free on orders over A$286.52. Trackable service: delivery in 7–14 days, with the tracking number sent by email. These are estimated delivery times, not guaranteed arrival dates.
Australian cities and delivery information
The Australian delivery options above apply to the destinations below. A city listing does not indicate a physical pharmacy branch or local stock.
| City | State or territory |
|---|---|
| Sydney | New South Wales |
| Melbourne | Victoria |
| Brisbane | Queensland |
| Perth | Western Australia |
| Adelaide | South Australia |
| Hobart | Tasmania |
| Gold Coast | Queensland |
| Canberra | Australian Capital Territory |
| Cairns | Queensland |
| Central Coast | New South Wales |
| Townsville | Queensland |
| Darwin | Northern Territory |
| Newcastle | New South Wales |
| Geelong | Victoria |
| Gladstone | Queensland |
| Port Macquarie | New South Wales |
| Bathurst | New South Wales |
| Forbes | New South Wales |
| Geraldton | Western Australia |
| Goulburn | New South Wales |
