Theophylline
Theophylline
- You can buy theophylline without a prescription in pharmacies across Australia, with fast shipping options available.
- Theophylline is primarily used to treat asthma and chronic obstructive pulmonary disease (COPD). It works by relaxing the muscles around the airways, making it easier to breathe.
- The usual dose of theophylline varies and is often between 300 mg to 600 mg per day, depending on the specific condition and patient response.
- The form of administration is oral tablets or liquid form.
- The effect of the medication typically begins within 30–60 minutes of ingestion.
- The duration of action is approximately 6–8 hours.
- It is advised to avoid alcohol while taking theophylline due to potential interactions that can increase side effects.
- The most common side effect is insomnia.
- Would you like to try theophylline without a prescription?
Basic Theophylline Information
- INN (International Nonproprietary Name): Theophylline
- Brand Names Available in Australia: Theophylline Sandoz
- ATC Code: R03DA04
- Forms & Dosages: Tablets (250mg, 500mg), Liquid (100mg/5ml)
- Manufacturers in Australia: Alphapharm, Arrow Pharmaceuticals
- Registration Status in Australia: Approved and listed on PBS
- OTC / Rx Classification: Prescription (Rx)
International Nonproprietary Name (INN)
Theophylline is the name assigned to this widely used medication that plays a crucial role in managing respiratory conditions. This compound is particularly beneficial for individuals suffering from asthma or chronic obstructive pulmonary disease (COPD). Theophylline acts to relax the muscles surrounding the airways, making it easier to breathe. It's renowned for its bronchodilator properties, meaning it helps expand the air passages in the lungs.Brand Names, Packaging, and Local Terminology
In Australia, Theophylline encompasses various brand names, each designed to cater to different patient needs.| Country | Brand Name(s) | Forms & Packaging | Local Term(s) |
|---|---|---|---|
| Australia | Theophylline Sandoz | Tablets (250mg, 500mg), Liquid | Theophylline |
| USA | Theo-24 | Extended-release capsules (100mg, 400mg) | Theophylline |
| Germany | Unifyl | Tablets (100mg, 200mg) | Theophylline |
| UK | Theophyllex | Tablets (200mg) | Theophylline |
| New Zealand | Theophylline Accord | Oral solution (100mg/5ml) | Theophylline |
ATC Code & Classification
The ATC code for Theophylline is R03DA04, which signifies its classification within the respiratory system medications, specifically aimed at treating obstructive airway diseases. This code categorises Theophylline under methylxanthines, a class known to effectively alleviate breathing difficulties.Forms, Dosages, and Formulation Table
Patients can find Theophylline in various forms, accommodating different needs and preferences:| Formulation Type | Strength(s) | Common Packaging |
|---|---|---|
| Tablets | 100mg, 250mg, 500mg | Blisters (20, 30) |
| Syrup/Solution | 100mg/5ml | Bottles (60ml, 100ml) |
| Injectable/Vials | 250mg/5ml | Vials (1, 5, or 10 doses) |
Local Manufacturers and Global Suppliers
The following manufacturers play a key role in supplying Theophylline across Australia: - Global players include Pfizer, GlaxoSmithKline, Mylan, and Sandoz. - Australia-specific manufacturers such as Alphapharm and Arrow Pharmaceuticals ensure local availability. Both local and global suppliers contribute to the accessibility of Theophylline, making it easier to manage respiratory conditions.Regulatory & Registration Status
Theophylline holds various approvals, which guarantee its safety and efficacy:| Regulatory Agency | Status | Sources/Notes |
|---|---|---|
| TGA (Australia) | Approved | Listed on PBS for specific indications |
| FDA (USA) | Approved | Rx only |
| EMA (European Union) | Approved | Available widely throughout the EU |
Standard Dosages
Dosages for Theophylline vary based on the individual’s condition: | Indication | Adult Dose | Pediatric Dose | Frequency | |--------------------------|--------------------------|------------------------------------|-------------------| | Asthma/COPD | 200-600mg daily divided | 5-10mg/kg daily divided | 2-4 times/day | | Apnoea in infants | 5-6mg/kg, adjusted based on response | Not routinely prescribed | Daily | Adjustments are essential for safe and effective treatment.Dosage Adjustments
Personalised dosing is critical for Theophylline to ensure safety and efficacy: - For children, dosing is typically based on weight, with close monitoring advised. - The elderly may require reduced doses due to potential decreased clearance. - Individuals with liver or kidney impairments may need dose reductions; always consult a healthcare provider.Overall, Theophylline demonstrates significant promise for managing respiratory conditions. Information about its brand names, regulatory status, and dosage considerations helps ensure safe usage while providing patients and healthcare professionals with clarity on how best to utilise this valuable medication.
Additional Precautions
When considering theophylline as a treatment option, there are several critical warnings and restrictions to keep in mind. Certain groups may need extra caution regarding side effects or interactions with other medications.
Critical Warnings & Restrictions
- High-risk Groups:
- Elderly: It's essential to monitor this demographic closely for potential side effects and interactions, often considering lower starting doses.
- Pregnant Women: A healthcare provider's input is crucial; any benefits must outweigh risks before using theophylline during pregnancy.
- Chronic Illness: Patients with existing health conditions, especially cardiac issues, require close monitoring.
Interaction with Activities
Patients living with theophylline may experience side effects that impact their daily activities:
- Driving: Possible side effects like dizziness or fatigue can affect driving abilities. It’s advisable to avoid driving until familiar with how the drug affects them.
- Workplace Safety: Being alert is essential when operating machinery, particularly during the initiation of therapy or when adjusting doses.
Micro-FAQ
Q: Can I drive after taking it in Australia?
A: It's recommended to assess how theophylline affects you before driving. Consulting a doctor if uncertain is also wise.
Components of Theophylline
The active component of theophylline is a methylxanthine compound, widely recognised for its role as a bronchodilator, helping to open airways in the lungs. Recent pharmacological studies are exploring its biosynthetic roles, particularly regarding its influence on cyclic AMP, which is vital for various cellular processes.
Administration Methods
Theophylline comes in several effective administration forms.
- Oral Tablets: These are primarily used for managing chronic respiratory conditions and typically taken regularly.
- Liquid Formulation: Often for dose adjustments based on weight, particularly useful in paediatric cases.
Safety Information and Recommendations
Using theophylline comes with some safety information worth noting:
- Contraindications: Severe allergies to theophylline, active peptic ulcer disease, arrhythmias, and recent myocardial infarction necessitate extreme caution.
- Relative Contraindications: Caution is advised for patients with liver impairment or hyperthyroidism, as well as those who have conditions that increase the risk of heart palpitations.
Monitoring and Follow-Up
Effective treatment with theophylline requires diligent monitoring:
- Clinical Monitoring: Early stages of treatment should involve regular checks for efficacy and toxicity.
- Laboratory Tests: It’s standard to monitor serum theophylline levels, especially when dosages are adjusted or when starting new medications.
Pharmacovigilance and Reporting
Adverse event reporting is crucial in the context of theophylline treatment:
- Adverse Event Reporting: Patients should feel encouraged to inform healthcare providers about any side effects or suspected allergic reactions.
- Medication Review Services: Advocate for regular medication review appointments that ensure safe and effective treatment management.
Regulatory Compliance and Trends
Staying on top of regulations is key to ensuring safe and effective use of theophylline, a medication often prescribed for respiratory conditions.
Recent Updates
Checking for updates on PBS listings and any changes in TGA guidelines regarding the use of theophylline is important. Those involved in patient care should regularly consult the Therapeutic Goods Administration (TGA) website. This is especially crucial with emerging evidence and practices.
Pharmacovigilance Trends
There’s been a noticeable increase in focus on pharmacovigilance over the last two years, particularly regarding patient-reported outcomes and side effects. Healthcare professionals are encouraged to gather insights from patients about their experiences with theophylline. Side effects can vary greatly, and understanding these from a patient's perspective can aid in better management of therapy.
Patient Education Materials
When it comes to managing medication like theophylline, making sure patients are informed is paramount.
Informed Consent Forms
It's essential to provide comprehensive patient education regarding the risks and benefits of therapy with theophylline, including possible alternative treatments. Informed consent forms should explain everything clearly to ensure patients understand their treatment options.
Adherence Tools
Using helpful tools like pill organisers can significantly manage medication schedules. This simple step can make a world of difference in ensuring adherence to prescribed theophylline regimens. Patients often benefit from reminders and an organised approach to their medications.
FAQs and Common Concerns
Common concerns regarding theophylline use often arise when patients or caregivers seek clarity about symptoms and lifestyle impacts.
Concerns Regarding Overdose
It's crucial to educate patients on the signs of theophylline overdose, such as nausea, vomiting, restlessness, and arrhythmias. Emphasising the immediate necessity of seeking medical help if these symptoms arise can potentially save lives and prevent severe complications.
Lifestyle Modifications
Encouraging a balanced diet while highlighting the need to avoid significant caffeine intake is important, as caffeine can increase the effects of theophylline. This approach not only reduces potential side effects but also supports overall health in asthmatic patients.
Public Health Information
Raising awareness about the importance of asthma management, particularly the role of theophylline, can empower communities.
Awareness Campaigns
Potential initiatives aimed at raising awareness about asthma management can spotlight theophylline's role in treatment. Campaigns can engage healthcare providers and patients in discussions about effective management strategies, ensuring patients know their options.
Community Support Groups
Integrating resources for patient support networks within respiratory health frameworks can also be beneficial. Ensuring patients have access to support groups fosters community, allowing for shared experiences and further education regarding theophylline.
Future Research Directions
Future developments in the field of respiratory health and theophylline usage are promising and paramount to improving treatment outcomes.
Ongoing Clinical Trials
Monitoring ongoing clinical trials that evaluate the efficacy of theophylline within diverse populations provides essential data. Comparing outcomes with biologic therapies can help identify the best treatment pathways for different patient groups.
Potential for New Formulations
There's also exciting potential for the development of extended-release formulations of theophylline. These innovations can significantly enhance patient compliance and overall comfort, allowing for more effective long-term management of respiratory conditions.
Delivery Information
| City | Region | Delivery Time |
|---|---|---|
| Sydney | New South Wales | 5–7 days |
| Melbourne | Victoria | 5–7 days |
| Brisbane | Queensland | 5–7 days |
| Perth | Western Australia | 5–7 days |
| Adelaide | South Australia | 5–7 days |
| Canberra | Australian Capital Territory | 5–7 days |
| Gold Coast | Queensland | 5–9 days |
| Newcastle | New South Wales | 5–9 days |
| Wollongong | New South Wales | 5–9 days |
| Geelong | Victoria | 5–9 days |
| Cairns | Queensland | 5–9 days |
| Toowoomba | Queensland | 5–9 days |
