Basic Uniphyl Cr Information

• INN (International Nonproprietary Name): Theophylline
• Brand names available in Australia: Uniphyl, Theo-24, Elixophyllin
• ATC Code: R03DA04
• Forms & dosages: Extended-release tablets (100 mg, 200 mg, 250 mg, 300 mg, 400 mg, 450 mg, 600 mg), oral solution (80 mg/15 mL)
• Manufacturers in Australia: Medicis
• Registration status in Australia: Approved prescription medicine
• OTC / Rx classification: Prescription only (Rx)

Critical Warnings & Restrictions

When considering Uniphyl for treatment, it’s essential to identify high-risk groups. This includes the elderly, pregnant individuals, and those with chronic illnesses. Each of these populations requires special attention prior to prescription as they are more susceptible to side effects and complications.

High-risk Groups (Elderly, Pregnancy, Chronic Illness)

- Elderly: Should receive lower dosages and careful monitoring due to increased sensitivity. - Pregnancy: Theophylline can affect the fetus; hence, a thorough risk-benefit assessment is necessary. - Chronic illnesses: Conditions like liver impairment or heart disease may necessitate dosing adjustments.

Interaction With Activities (Driving, Workplace Safety Under Australian Law)

Uniphyl can influence cognition and physical performance, leading to potential hazards, especially while driving or operating machinery. Side effects such as dizziness and palpitations might affect coordination and reaction times, important factors for workplace safety. Therefore, individuals should assess their response to the medication before engaging in activities requiring full alertness.

Q&A — “Can I Drive After Taking It In Australia?”

Driving after taking Uniphyl is conditionally safe; however, it is vital to consider individual responses to the drug. If one experiences dizziness, severe fatigue, or any other side effects impacting focus, it is advisable to refrain from driving. Australian law mandates maintaining a duty of care on the roads, so always prioritise safety over convenience when on medication.

Usage Basics

Theophylline is administered under several brand names in Australia; most notably, Uniphyl is the primary option available in pharmacies. Its status as a TGA-approved medication signifies that it meets Australian safety, quality, and efficacy standards.

INN, Brand Names Available in Australia

The Theophylline market features various brands aside from Uniphyl, including:

• Theo-24
• Elixophyllin
• Theochron

Legal Classification (TGA-Approved, PBS-Listed)

The Therapeutic Goods Administration (TGA) classifies Uniphyl as a prescription medication, ensuring it is dispensed under regulated conditions. A listing under the Pharmaceutical Benefits Scheme (PBS) means patients can access subsidised medication, improving affordability and continuing care for those with asthma and COPD.

Dosing Guide

The dosing of Uniphyl should be tailored according to health conditions, age, and any comorbidities. Recommended dosages generally range from 300 mg to 600 mg per day for adults, often administered in extended-release forms to ensure steady medication levels.

Standard Regimens (PBS Reference Dosing)

For asthma and COPD maintenance: - Adults typically receive 300 mg to 600 mg daily. - Children are dosed based on weight, starting from 10 to 13 mg/kg/day.

Adjustments for Comorbidities

- Elderly: Begin at the lower end of the dosing range, adjusting based on tolerance. - Liver impairment: Requires a significant dosage reduction—monitoring serum levels is critical. - Renal impairment: May need dose adjustments as kidney function impacts elimination.

If a dose is missed, it’s advisable to take it as soon as remembered; however, skip the dose if the next one is near. Never double up doses, as this could lead to adverse reactions or toxicity.

Interaction Chart

Certain food and drink interactions can affect the efficacy and safety of Uniphyl. For example, excessive consumption of caffeine or alcohol may exacerbate side effects, making moderate intake crucial for patients on Theophylline.

Food and Drinks (Alcohol, Coffee, Australian Diet Context)

- Caffeine: Found in coffee and tea, can amplify Theophylline side effects. - Alcohol: May increase risks associated with Uniphyl, impacting liver function and exacerbating side effects.

Common Drug Conflicts

Monitoring for potential interactions is essential. Medications like macrolide antibiotics or certain antiepileptics can interfere with Theophylline metabolism. Always consult healthcare providers for guidance on medication combinations to ensure safety.

User Reports & Trends

Feedback from Australia's online pharmacy platforms reveals varied patient experiences with Uniphyl. Many users highlight its efficacy in managing asthma symptoms alongside reported side effects such as mild insomnia and gastrointestinal discomfort.

Trends show a general satisfaction with the medication, especially when used consistently as directed. However, monitoring for adverse effects remains a common theme in patient discussions on health forums and review sites.

Access & Purchase Options

Finding a reliable source for Uniphyl can be a concern for many patients managing chronic asthma or COPD. One option is to visit national pharmacy chains like Chemist Warehouse, Priceline, and TerryWhite. These pharmacies typically stock Uniphyl in various dosages, including the extended-release form of theophylline, which can be convenient for patients.

The average pricing for Uniphyl at these outlets generally falls within the $30 to $50 range for a month's supply, but prices may vary based on location and specific promotions. Availability is usually good, ensuring that patients can easily access their medications whenever they need them.

Online pharmacies and telehealth e-prescriptions

Online pharmacies are an increasingly popular choice for those seeking to buy Uniphyl without the hassle of visiting a physical location. Many of these platforms now offer telehealth services, allowing patients to consult with healthcare professionals and obtain e-prescriptions seamlessly. The process generally involves a brief online consultation, where patients discuss their symptoms and treatment options with a licensed doctor.

Once the e-prescription is issued, patients can conveniently order Uniphyl from the online pharmacy. This method not only saves time but also affords greater privacy and discretion, making it a desirable option for many users. Such advancements in telehealth access ensure that more individuals can receive the necessary medications without unnecessary delays.

Mechanism & Pharmacology

Simplified explanation

Uniphyl contains theophylline, which acts as a bronchodilator. In simpler terms, it helps to relax the airways in the lungs, making it easier for patients to breathe. This is especially beneficial for individuals suffering from asthma or chronic obstructive pulmonary disease (COPD). Theophylline works by inhibiting certain enzymes and blocking specific receptors that lead to airway constriction.

Clinical terms

Key clinical terms associated with Uniphyl include:

• Bronchodilator: A substance that helps widen the air passages, improving airflow.
• Airway disease: Conditions like asthma and COPD that affect normal breathing.
• Therapeutic monitoring: Regular checks to ensure drug levels remain within a safe and effective range.

These terms illustrate how Uniphyl effectively supports patients in managing their respiratory conditions.

Indications & Off-Label Uses

Approved indications by TGA

The Therapeutic Goods Administration (TGA) has approved Uniphyl for use in managing chronic asthma and chronic obstructive pulmonary disease (COPD). The medication serves as an effective maintenance treatment, helping to control symptoms and improve quality of life for those affected by these conditions.

Off-label uses in Australian clinical practice

While primarily prescribed for asthma and COPD, some Australian healthcare providers may also prescribe Uniphyl for off-label uses. These may include situations like exercise-induced bronchospasm or more severe respiratory distress scenarios. Such practices are less formally documented but highlight the medication's versatility in clinical settings.

Key Clinical Findings

Recent studies conducted from 2022 to 2025 have provided valuable insights into the effectiveness and safety of Uniphyl in treatment protocols. In Australia, investigations showed that theophylline remains a relevant option in maintenance therapy for asthma and COPD, particularly for patients unresponsive to other treatments.

International research has echoed these findings, noting that Uniphyl offers distinct advantages in terms of its affordability and once-daily dosing convenience. This makes it an attractive choice for patients aiming to manage their conditions without excessive medication complexities.

Such investigations underline the importance of balanced approaches to treatment, focusing not just on effectiveness but also on improving patient compliance and quality of life.

Alternatives Matrix

PBS-listed alternatives comparison table

Pros and cons checklist

• Pros: Affordable, effective, once-daily dosing.
• Cons: Narrow therapeutic index, potential interactions.

Common Questions

Patients often raise concerns during pharmacy consultations regarding Uniphyl CR. Here are some frequently asked questions:

• What side effects should I watch for? Users may experience nausea, insomnia, or headache. In cases of severe symptoms like palpitations or seizures, medical assistance is crucial.
• How effective is Uniphyl CR for asthma and COPD? The medication has shown to be effective in managing chronic asthma and COPD, especially for patients unresponsive to inhaled treatments.
• What should I do if I miss a dose? It's advisable to take the missed dose when remembered, unless it's near the time for the next dose. Doubling up is not recommended.
• How can I ensure proper adherence? Pharmacists recommend setting reminders, using pill organizers, and maintaining regular consultations to monitor dosage and efficacy.

These questions reflect common patient worries, highlighting the importance of clear communication during pharmacy consultations.

Suggested Visual Content

Visual aids can significantly enhance the understanding of Uniphyl CR. Suggested infographics include:

• PBS Pricing Guide: An illustrative overview of costs associated with Uniphyl CR, showing how subsidies affect affordability for patients.
• Pharmacy Network Map: A visual representation of pharmacy locations across Australia, aiding patients in locating nearby pharmacies that stock Uniphyl CR.
• Side Effects Overview: An easy-to-digest infographic detailing common side effects, helping patients recognize what to expect.

Registration & Regulation

TGA approval

The registration of Uniphyl CR through the Therapeutic Goods Administration (TGA) involves comprehensive compliance and safety assessments. These evaluations ensure that the medication meets necessary health and safety standards, facilitating its availability in Australia.

PBS subsidy details

With the Pharmaceutical Benefits Scheme (PBS) subsidy, patients gain significant financial relief when accessing Uniphyl CR. The PBS subsidises medications based on clinical need, making essential treatments affordable. This scheme specifically benefits those with chronic conditions requiring ongoing management, thus enhancing patient access.

Storage & Handling

Household storage in Australian climate

For optimal preservation of Uniphyl CR, proper storage is essential. Given Australia’s variable climate, it is recommended to:

• Store in a cool, dry place, ideally at a temperature ranging between 20–25°C.
• Avoid exposure to heat and humidity.
• Keeps the medication in its original container, tightly closed, to prevent moisture damage.

Cold-chain handling for pharmacies

Pharmacies must adhere to strict handling protocols to maintain the quality of Uniphyl CR. This includes:

• Ensuring transportation is appropriate to keep the medication within required temperature ranges.
• Regularly checking storage conditions and conducting audits to comply with health guidelines.

Guidelines for Proper Use

Australian pharmacist counselling style

When counselling patients on the proper use of Uniphyl CR, Australian pharmacists focus on clear communication. They emphasise:

• The importance of adhering to prescribed dosing schedules.
• Recognising potential side effects and when to seek advice.
• Offering tips for managing symptoms effectively.

Patient advice from PBS and national health authorities

Reliable sources, including the PBS and national health authorities, provide essential guidance on the responsible use of Uniphyl CR. Patients are advised to:

• Understand their condition and treatment plan.
• Keep regular follow-up appointments.
• Communicate openly about any side effects experienced.